Axe + Clockwerk

Why this works

Setting up a gank with these two heroes relies on a specific sequence. Clockwerk can initiate with Hookshot from a long way out, isolating a target in Power Cogs for Axe to follow up on. Axe can then Blink in and use Berserker's Call on any nearby enemies who try to help, turning a single pick-off into a wider teamfight. The main issue is that their kits can actively work against each other. A poorly timed or placed set of Cogs can easily knock enemies out of Axe's Blink or Call range, completely whiffing the whole engagement. This makes their combined initiation feel inconsistent.

Across the game, the success of this pair comes down to communication. If Axe and Clockwerk go on different targets, they can sometimes split the enemy's attention effectively. If they both try to jump the same hero, they're often committing too many resources for one kill, leaving the rest of their team vulnerable. Enemies will counter this by building Force Staffs and other escape items, making the job for both initiators much harder. Because they don't have a guaranteed way to chain their abilities together, their success often depends more on player skill than on any natural synergy between their spells.