Mirana + Outworld Destroyer

Why this works

Drafting Mirana and Outworld Destroyer together often comes down to how much you value one specific ganking combination. Outworld Destroyer’s Astral Imprisonment provides a perfect, telegraphed setup for Mirana to land a Sacred Arrow from any distance. There's no guesswork involved; the target is held in place, allowing for an easy stun and a follow-up Starstorm. This creates a very long duration of single-target lockdown that can secure a kill on an isolated hero from the early mid-game onward. The reliability of this one interaction is the main draw for pairing these two heroes.

Outside of that specific setup, their abilities don't have much direct overlap. Both heroes are good at picking off single targets, but they don't necessarily amplify each other's strengths in a wider teamfight. Mirana might use Moonlight Shadow to help the team get in position, but that helps everyone, not OD in particular. Once a big fight breaks out, they tend to function as two separate damage dealers going after their own targets. Because their synergy is so focused on that one lockdown combo, their overall performance together depends heavily on their ability to find and execute those pickoffs throughout the game.