Phantom Assassin + Pugna

Why this works

Trying to burst a target with Phantom Assassin often runs into a conflict with what Pugna wants to do. The core issue is Decrepify. While Pugna can use it to save PA from a physical carry by making her ethereal, it's often used on an enemy to set up his own magic damage from Nether Blast and Life Drain. This is a problem for Phantom Assassin, as she deals purely physical damage and can't attack the Decrepified target. The result is a non-combo where one hero's main burst setup directly disables the other's ability to contribute damage to that same target.

This means success often comes down to precise coordination. Pugna needs to play a more defensive role, holding Decrepify for Phantom Assassin when she gets jumped, rather than using it offensively. He can still contribute by pushing lanes with Nether Blast to create space for her to farm, and his Nether Ward is helpful against spell-heavy teams that might otherwise kite her. In chaotic teamfights, however, it's very easy to mistime Decrepify and ruin a kill attempt. This reliance on perfect execution and the clashing damage types keeps the partnership from being consistently effective.