Earthshaker + Witch Doctor

Why this works

Getting caught by a long-range Fissure is uncomfortable, but it's the follow-up that spells trouble. Earthshaker provides the lockdown, either with a single-target trap or a multi-hero Echo Slam. This creates a perfect window for Witch Doctor to apply Maledict, amplifying all incoming damage. With the enemy stunned and cursed, Witch Doctor can then channel Death Ward from a safe distance, often securing a kill before the stun even wears off. The combination of long-range initiation, lockdown, damage amplification, and sustained damage can be very effective at picking off key targets before a fight properly begins.

However, this entire sequence is fragile and requires good positioning from both heroes. The combo relies heavily on Earthshaker landing a good initiation, which often requires a Blink Dagger. Meanwhile, Witch Doctor is a prime target for the enemy team, and his Death Ward can be canceled by any stray stun. If the enemy team has good vision and initiates on the Witch Doctor first, the synergy completely falls apart. Success often comes down to which team gets the jump, making the pair effective when they have the momentum but weak when playing from behind.