Vyper Synergies

Vyper wants a partner who can convert her early pressure into kills and hold ground once the fight opens up. Victor pairs well because he can lock targets in place while Vyper closes the gap, turning a small advantage into a clean pickoff before the enemy regroups. Seven brings the follow-up damage to finish what Vyper starts, and Kelvin keeps her healthy enough to stay aggressive through the midgame. What Vyper offers back is tempo, dragging fights onto her terms so her teammates can commit with confidence.

Vyper wins 48.88% of matches overall (#23 of 38 heroes) since the Matchmaking Update. Its best duo is Seven — together they win 55.72%; the weakest pairing is Silver at 42.50%.

Best teammates for Vyper

Hero	Win Rate	Matches
Seven	55.72%	7,112
Victor	54.25%	7,182
McGinnis	54.00%	6,485
Ivy	53.36%	8,741
Graves	53.31%	10,438
Kelvin	52.18%	5,836
Lash	52.07%	12,934
Paige	51.55%	10,087
Calico	51.42%	7,197
Vindicta	50.99%	7,142
Drifter	50.43%	11,484
Dynamo	50.39%	8,708
Mo & Krill	50.26%	12,664

Weakest pairings for Vyper

Hero	Win Rate	Matches
Silver	42.50%	6,750
Sinclair	43.26%	5,044
Mina	43.96%	7,779
Mirage	44.05%	4,157
Venator	44.21%	7,398
Pocket	44.92%	7,115
The Doorman	45.10%	5,612
Paradox	46.14%	8,516
Shiv	46.15%	9,766
Bebop	46.17%	14,037
Yamato	46.21%	7,230
Rem	46.25%	11,118
Grey Talon	47.03%	4,416
Holliday	47.11%	7,535
Viscous	47.94%	8,286
Celeste	48.32%	9,936
Infernus	48.35%	11,231
Apollo	48.49%	7,669
Haze	48.54%	6,611
Wraith	48.84%	7,605
Billy	49.12%	12,264
Warden	49.45%	4,944
Abrams	49.63%	11,885
Lady Geist	49.94%	6,336

Stats since the Matchmaking Update. Data updated Aug 8, 2026.